BDBM50303422 6-(3-chlorophenylamino)-9-cyclopentyl-9H-purine-2-carbonitrile::CHEMBL578162::cid_44142124

SMILES Clc1cccc(Nc2nc(nc3n(cnc23)C2CCCC2)C#N)c1

InChI Key InChIKey=SKIHJAAPCWIBJZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303422   

TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303422(6-(3-chlorophenylamino)-9-cyclopentyl-9H-purine-2-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303422(6-(3-chlorophenylamino)-9-cyclopentyl-9H-purine-2-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed