BDBM50303448 Beta-elemonic acid::CHEMBL566929
SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6@@H](-[#6@H]1-[#6]-[#6][C@]2([#6])[#6]-3=[#6](-[#6]-[#6][C@@]12[#6])[C@@]1([#6])[#6]-[#6]-[#6](=O)C([#6])([#6])[#6@H]1-[#6]-[#6]-3)-[#6](-[#8])=O
InChI Key InChIKey=XLPAINGDLCDYQV-DXXDIINSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50303448
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by HPLC an...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 5 min...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite Louis Pasteur
Curated by ChEMBL
Universite Louis Pasteur
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair