BDBM50303585 1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)-3-(4-chlorophenyl)urea::CHEMBL583263
SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)cc2)n(n1)-c1cccc(c1)[N+]([O-])=O
InChI Key InChIKey=QMJQHTTXRJIVJD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50303585
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Technical University Of Dortmund
Curated by ChEMBL
Technical University Of Dortmund
Curated by ChEMBL
Affinity DataIC50: 856nMAssay Description:Inhibition of wild type DDR2 (unknown origin) preincubated for 30 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Chemical Genomics Centre Of The Max Planck Society
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Technical University Of Dortmund
Curated by ChEMBL
Technical University Of Dortmund
Curated by ChEMBL
Affinity DataKd: 412nMAssay Description:Binding affinity to human acrylodan-labeled N-terminal His-tagged DDR2 (558 to 855 aa) by FLiK assayMore data for this Ligand-Target Pair