BDBM50304356 2-methyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-6-carboxamide::CHEMBL611953

SMILES Cc1ccc2[nH]c3C(CCCCc3c2c1)C(N)=O

InChI Key InChIKey=BEGPLEUQYHEHLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304356   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50304356(2-methyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human full length SIRT1 expressed in DE3 cells by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304356(2-methyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed