BDBM50304778 3-(3-chloro-4-(3-(cyclobutylmethylsulfonyl)-4-hydroxyphenoxy)-5-methylphenylamino)-3-oxopropanoic acid::CHEMBL594047

SMILES Cc1cc(NC(=O)CC(O)=O)cc(Cl)c1Oc1ccc(O)c(c1)S(=O)(=O)CC1CCC1

InChI Key InChIKey=HCQUAEYYTNDJIM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304778   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304778(3-(3-chloro-4-(3-(cyclobutylmethylsulfonyl)-4-hydr...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to thyroid receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304778(3-(3-chloro-4-(3-(cyclobutylmethylsulfonyl)-4-hydr...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to thyroid receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed