BDBM50305108 (+/-)-N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-(1-oxo-1,2,3,7,8,9-hexahydropyrano[3,2-e]isoindol-8-yl)benzamide::CHEMBL593281

SMILES Fc1ccc2[nH]cc(CCCN(C3COc4ccc5CNC(=O)c5c4C3)C(=O)c3ccccc3)c2c1

InChI Key InChIKey=DSNDRFNBUJSXEM-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305108   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305108((+/-)-N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-(1-ox...)
Affinity DataKi:  31nMAssay Description:Displacement of labeled paroxetine from 5-HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305108((+/-)-N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-(1-ox...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305108((+/-)-N-(3-(5-fluoro-1H-indol-3-yl)propyl)-N-(1-ox...)
Affinity DataEC50:  436nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed