BDBM50305111 (+/-)-8-(4-(5-fluoro-1H-indol-3-yl)butylamino)-2,3,8,9-tetrahydropyrano[3,2-e]isoindol-1(7H)-one::CHEMBL595622

SMILES Fc1ccc2[nH]cc(CCCCNC3COc4ccc5CNC(=O)c5c4C3)c2c1

InChI Key InChIKey=SDTOSYQWYBTBGQ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305111   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305111((+/-)-8-(4-(5-fluoro-1H-indol-3-yl)butylamino)-2,3...)
Affinity DataKi:  20nMAssay Description:Displacement of labeled paroxetine from 5-HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305111((+/-)-8-(4-(5-fluoro-1H-indol-3-yl)butylamino)-2,3...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305111((+/-)-8-(4-(5-fluoro-1H-indol-3-yl)butylamino)-2,3...)
Affinity DataEC50:  284nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed