BDBM50305566 CHEMBL585961::N-(5-bromothiazol-2-ylcarbamoyl)-6,7-dihydro-4H-thieno[3,2-c]pyran-2-sulfonamide

SMILES Brc1cnc(NC(=O)NS(=O)(=O)c2cc3COCCc3s2)s1

InChI Key InChIKey=WGBGKFSPGAVVBQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305566   

TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305566(CHEMBL585961 | N-(5-bromothiazol-2-ylcarbamoyl)-6,...)
Affinity DataIC50:  350nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305566(CHEMBL585961 | N-(5-bromothiazol-2-ylcarbamoyl)-6,...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305566(CHEMBL585961 | N-(5-bromothiazol-2-ylcarbamoyl)-6,...)
Affinity DataIC50:  530nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed