BDBM50305587 CHEMBL589137::N-(5-bromothiazol-2-ylcarbamoyl)-3-ethylbenzenesulfonamide::N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-3-ethylbenzenesulfonamide

SMILES CCc1cccc(c1)S(=O)(=O)NC(=O)Nc1ncc(Br)s1

InChI Key InChIKey=CDARLLLKPJHKBU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305587   

TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305587(CHEMBL589137 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305587(CHEMBL589137 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305587(CHEMBL589137 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair