BDBM50305817 1-(4-phenoxybenzyl)-5-(trifluoromethoxy)indoline-2,3-dione::CHEMBL604482::cid_44602489

SMILES FC(F)(F)Oc1ccc2N(Cc3ccc(Oc4ccccc4)cc3)C(=O)C(=O)c2c1

InChI Key InChIKey=HRSJEMJKLHWGLF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305817   

TargetMuscarinic acetylcholine receptor M1(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50305817(1-(4-phenoxybenzyl)-5-(trifluoromethoxy)indoline-2...)
Affinity DataEC50:  1.32E+4nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Muscarinic acetylcholine receptors are family A GPCRs comprised of...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50305817(1-(4-phenoxybenzyl)-5-(trifluoromethoxy)indoline-2...)
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation activity at muscarinic M5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50305817(1-(4-phenoxybenzyl)-5-(trifluoromethoxy)indoline-2...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human muscarinic M5 expressed in CHO cells assessed as stimulation of calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed