BDBM50307127 (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE::(Z)-N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide::CHEMBL605003::N,N-dimethyl-2-oxo-3-((4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)indoline-5-sulfonamide::SU-6656
SMILES CN(C)S(=O)(=O)c1ccc2NC(=O)\C(=C/c3cc4CCCCc4[nH]3)c2c1
InChI Key InChIKey=LOGJQOUIVKBFGH-YBEGLDIGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50307127
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 6.88E+5nMAssay Description:Inhibition of c-SrcChecked by AuthorMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of SrcChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of FynChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Yes kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Lyn kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Milano-Bicocca
Curated by ChEMBL
University Of Milano-Bicocca
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of FLT3 by ELISA-based kinase assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Milano-Bicocca
Curated by ChEMBL
University Of Milano-Bicocca
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ABL by ELISA-based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of ALK by ELISA-based kinase assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Milano-Bicocca
Curated by ChEMBL
University Of Milano-Bicocca
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant His-tagged RET expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase BRSK2(Homo sapiens (Human))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of BRSK2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Aurora C in the presence of 5uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Aurora B in the presence of 20uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of Lck in the presence of 50uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of MST2 in the presence of 50uM ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair