BDBM50308777 1-(4-(3-Cyclopropyl-7-morpholino-3H-[1,2,3]-triazolo[4,5-d]pyrimidin-5-yl)phenyl)-3-(thiophen-2-yl)urea::CHEMBL601073
SMILES O=C(Nc1cccs1)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2nnn(C3CC3)c2n1
InChI Key InChIKey=FWYXLDROMMGZKZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50308777
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.05nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 19.5nMAssay Description:Inhibition of human PI3Kgamma by fluorescence polarization format assayMore data for this Ligand-Target Pair