BDBM50310148 BI-90H9::CHEMBL611079::N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine
SMILES COCCNc1nnc(Sc2ncc(s2)[N+]([O-])=O)s1
InChI Key InChIKey=BEWZDJYSVBMQJT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50310148
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Institute For Medical Research
Curated by ChEMBL
Institute For Medical Research
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Displacement of biotin-labeled pep-JIP1from JNK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute For Medical Research
Curated by ChEMBL
Institute For Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Institute For Medical Research
Curated by ChEMBL
Institute For Medical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
National Clinical Research Center For Geriatrics
Curated by ChEMBL
National Clinical Research Center For Geriatrics
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of JNK1 (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Bacillus anthracis anthrax lethal factorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
National Clinical Research Center For Geriatrics
Curated by ChEMBL
National Clinical Research Center For Geriatrics
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Institute For Medical Research
Curated by ChEMBL
Institute For Medical Research
Curated by ChEMBL
Affinity DataKd: 2.80E+3nMAssay Description:Inhibition of wild-type JNK2 by isothermal calorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FURINMore data for this Ligand-Target Pair