BDBM50310155 2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyridin-4-yl)-1H-imidazol-5(4H)-one::CHEMBL604590::rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyridin-4-yl)-1H-imidazol-5(4H)-one

SMILES CN1C(N)=NC(C1=O)(c1ccncc1)c1cccc(c1)-c1cccnc1

InChI Key InChIKey=AIKOTXHNUIYVMD-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50310155   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyr...)
Affinity DataIC50:  60nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyr...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyr...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyr...)
Affinity DataIC50:  480nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310155(2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-(pyr...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair