BDBM50310161 CHEMBL597073::rac-2-amino-4-(2-isopropyl-6-methylpyridin-4-yl)-1-methyl-4-(3-(pyrimidin-5-yl)phenyl)-1H-imidazol-5(4H)-one

SMILES CC(C)c1cc(cc(C)n1)C1(N=C(N)N(C)C1=O)c1cccc(c1)-c1cncnc1

InChI Key InChIKey=VXCKGUCJPIJYJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310161   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50310161(CHEMBL597073 | rac-2-amino-4-(2-isopropyl-6-methyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed