BDBM50310301 CHEMBL599742::N,N'-(ethane-1,2-diyl)bis(N-ethyl-3,4-dihydroxybenzenesulfonamide)::US9120744, CDE-032

SMILES CCN(CCN(CC)S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1

InChI Key InChIKey=KULDNHPCSUYZFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50310301   

TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM50310301(CHEMBL599742 | N,N'-(ethane-1,2-diyl)bis(N-ethyl-3...)
Affinity DataIC50:  1.02E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAntithrombin-III(Homo sapiens (Human))
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50310301(CHEMBL599742 | N,N'-(ethane-1,2-diyl)bis(N-ethyl-3...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of antithrombin-3 assessed as residual alpha-thrombin activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM50310301(CHEMBL599742 | N,N'-(ethane-1,2-diyl)bis(N-ethyl-3...)
Affinity DataIC50:  9.32E+3nMAssay Description:Inhibition of human recombinant PAI1 assessed as rate of AMC release after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed