BDBM50312005 CHEMBL1087512::Lecanindole B

SMILES C[C@@]12[C@H](Cc3c1[nH]c1ccccc31)CC[C@@]1(O)C(C)(C)C(=O)CC[C@]21C

InChI Key InChIKey=JQTRPSHLFTZYHC-SESVXGAZSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50312005   

TargetAndrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312005(CHEMBL1087512 | Lecanindole B)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at androgen receptor ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luciferas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312005(CHEMBL1087512 | Lecanindole B)
Affinity DataIC50: >1.00E+7nMAssay Description:Antagonist activity at mineralocorticoid receptor ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312005(CHEMBL1087512 | Lecanindole B)
Affinity DataEC50:  0.300nMAssay Description:Activation of progesterone receptor in human T47D cells after 20 hrs by PRE-tagged luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312005(CHEMBL1087512 | Lecanindole B)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at estrogen receptor beta ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50312005(CHEMBL1087512 | Lecanindole B)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at estrogen receptor alpha ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed