BDBM50312153 1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea::CHEMBL1081198
SMILES FC(F)(F)c1cccc(NC(=O)Nc2cccc(c2)-c2cn3ccnc3c(NCc3ccncc3)n2)c1
InChI Key InChIKey=NWEIPABWNQPRCZ-UHFFFAOYSA-N
Data 26 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 50312153
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PKCalpha after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of Abl1 after 1 hrMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cgi Pharmaceuticals
Curated by ChEMBL
Cgi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of VEGFR3 after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ZAp70 after 1 hrMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cgi Pharmaceuticals
Curated by ChEMBL
Cgi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Cgi Pharmaceuticals
Curated by ChEMBL
Cgi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 747nMAssay Description:Inhibition of VEGFR1 after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Cgi Pharmaceuticals
Curated by ChEMBL
Cgi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Src after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Syk after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PKCtheta after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PKCbeta2 after 1 hrMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Cgi Pharmaceuticals
Curated by ChEMBL
Cgi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of PDGFRbeta after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Lyn after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of LCK after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Fyn after 1 hrMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cgi Pharmaceuticals
Curated by ChEMBL
Cgi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Flt3 after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FGFR4 after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of EPHA2 after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EGFR after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK5 after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of Btk after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Blk after 1 hrMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Cgi Pharmaceuticals
Curated by ChEMBL
Cgi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Akt after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IRK after 1 hrMore data for this Ligand-Target Pair