BDBM50313035 (Z)-4-(2-(4-methoxyphenyl)hydrazono)-3-(3,4,5-trimethoxyphenyl)-1H-pyrazol-5(4H)-one::CHEMBL1082157

SMILES COc1ccc(cc1)N=Nc1c([nH][nH]c1=O)-c1cc(OC)c(OC)c(OC)c1

InChI Key InChIKey=GWZNBRKYMGDYKF-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313035   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50313035((Z)-4-(2-(4-methoxyphenyl)hydrazono)-3-(3,4,5-trim...)Copy SMILESCopy InChI

Affinity DataKi:  9nMAssay Description:Inhibition of GSK3-beta assessed as NADH level after 10 mins by pyruvate kinase/lactate dehydrogenase coupled spectrophotometric assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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