BDBM50313175 (R)-2-((R)-1-ethyl-4-(4-isopropylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide::CHEMBL1080722

SMILES CCn1nc(C)c2[C@@H](CCc3ccc(cc3)C(C)C)N(CCc12)[C@@H](C(=O)NC)c1ccccc1

InChI Key InChIKey=IGOJZIQKSMEGBM-LEAFIULHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313175   

TargetOrexin receptor type 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313175((R)-2-((R)-1-ethyl-4-(4-isopropylphenethyl)-3-meth...)
Affinity DataIC50:  179nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313175((R)-2-((R)-1-ethyl-4-(4-isopropylphenethyl)-3-meth...)
Affinity DataIC50:  1.92E+3nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed