BDBM50314081 (3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-17-(4-guanidinobenzyl)-29-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-26-isobutyl-7,7,22,25-tetramethyl-1,9,12,15,18,21,24,27,30,31-decaoxodotriacontahydro-1H-pyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30]dithianonaazacyclotritriacontine-3-carboxamide::CHEMBL1089949

SMILES [#6]-[#6](-[#6])-[#6]-[#6@@H]-1-[#7](-[#6])-[#6](=O)-[#6]-[#7](-[#6])-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(cc2)\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#7]-[#6](-[#7])=[#7])-[#7]-[#6](-[#6])=O)C([#6])([#6])[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H]-2-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6]-1=O)-[#6](-[#7])=O)-[#6@@H](-[#6])-[#8]

InChI Key InChIKey=DFZNYFWFCYPCIR-RTUTXIKTSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314081   

TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314081((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314081((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Affinity DataKd:  74nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314081((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Affinity DataKd:  62nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed