BDBM50315136 CHEMBL1092240::N-(4-(1H-1,2,4-triazol-1-yl)phenyl)-5-nitro-6-(4-(pyridin-2-ylthio)piperidin-1-yl)pyrimidin-4-amine

SMILES [O-][N+](=O)c1c(Nc2ccc(cc2)-n2cncn2)ncnc1N1CCC(CC1)Sc1ccccn1

InChI Key InChIKey=XPABZYFJCKZPIF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315136   

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315136(CHEMBL1092240 | N-(4-(1H-1,2,4-triazol-1-yl)phenyl...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human GPR119 receptor by cAMP mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315136(CHEMBL1092240 | N-(4-(1H-1,2,4-triazol-1-yl)phenyl...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-expressing 6CRE-luciferase gene after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315136(CHEMBL1092240 | N-(4-(1H-1,2,4-triazol-1-yl)phenyl...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at GPR119 receptor by cell based cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed