BDBM50315136 CHEMBL1092240::N-(4-(1H-1,2,4-triazol-1-yl)phenyl)-5-nitro-6-(4-(pyridin-2-ylthio)piperidin-1-yl)pyrimidin-4-amine
SMILES [O-][N+](=O)c1c(Nc2ccc(cc2)-n2cncn2)ncnc1N1CCC(CC1)Sc1ccccn1
InChI Key InChIKey=XPABZYFJCKZPIF-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50315136
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Agonist activity at human GPR119 receptor by cAMP mobilization assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Agonist activity at human GPR119 receptor expressed in CHO-K1 cells co-expressing 6CRE-luciferase gene after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Agonist activity at GPR119 receptor by cell based cAMP assayMore data for this Ligand-Target Pair