BDBM50317657 3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]propane-1-sulfonic aciddimethylamide::CHEMBL1095864

SMILES CN(C)S(=O)(=O)CCCN1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=YFLHNDQJLWMBSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317657   

TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317657(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317657(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50:  3.70E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed