BDBM50317660 3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]propane-1-sulfonamide::CHEMBL1098173

SMILES Cc1cc(ccc1C#N)N1C(=S)N(CCCS(N)(=O)=O)C(C)(C)C1=O

InChI Key InChIKey=PSPOUNBCWIUTOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317660   

TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed