BDBM50319018 4-(5-(3-methoxybenzyl)-3-methylbenzo[b]thiophen-2-yl)pyrimidin-2-amine::CHEMBL1086544

SMILES COc1cccc(Cc2ccc3sc(c(C)c3c2)-c2ccnc(N)n2)c1

InChI Key InChIKey=ZGNMLTMSLMGZKE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319018   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319018(4-(5-(3-methoxybenzyl)-3-methylbenzo[b]thiophen-2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319018(4-(5-(3-methoxybenzyl)-3-methylbenzo[b]thiophen-2-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of ROCK1 assessed as ATP cunsumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed