BDBM50319021 3-((2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thiophen-5-yl)methyl)phenol::CHEMBL1082758

SMILES Cc1c(sc2ccc(Cc3cccc(O)c3)cc12)-c1ccnc(N)n1

InChI Key InChIKey=RVJGCFAHXOTBRF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319021   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319021(3-((2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thio...)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319021(3-((2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thio...)
Affinity DataIC50:  20nMAssay Description:Inhibition of ROCK1 assessed as ATP cunsumptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed