BDBM50319822 1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)piperazine::CHEMBL1085959

SMILES COc1ccccc1CC(N1CCNCC1)c1ccccc1F

InChI Key InChIKey=CLUGYQSXBJPTPD-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50319822   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319822(1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319822(1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319822(1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319822(1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319822(1-(1-(2-fluorophenyl)-2-(2-methoxyphenyl)ethyl)pip...)
Affinity DataIC50:  4.01E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed