BDBM50319826 1-(2-(2-(difluoromethoxy)phenyl)-1-(3-fluorophenyl)ethyl)piperazine::CHEMBL1084577

SMILES FC(F)Oc1ccccc1CC(N1CCNCC1)c1cccc(F)c1

InChI Key InChIKey=BGJYOLBNUMRPNE-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319826   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319826(1-(2-(2-(difluoromethoxy)phenyl)-1-(3-fluorophenyl...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319826(1-(2-(2-(difluoromethoxy)phenyl)-1-(3-fluorophenyl...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319826(1-(2-(2-(difluoromethoxy)phenyl)-1-(3-fluorophenyl...)
Affinity DataKi:  3.46E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319826(1-(2-(2-(difluoromethoxy)phenyl)-1-(3-fluorophenyl...)
Affinity DataIC50:  8.24E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed