BDBM50321040 CHEMBL1165318::{4-[1-(2,5-Difluoro-benzyl)-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazin-7-yl]-phenyl}-((S)-2-pyrrolidin-1-ylmethylpyrrolidin-1-yl)-methanone

SMILES Fc1ccc(F)c(CN2CCNc3ncc(cc23)-c2ccc(cc2)C(=O)N2CCC[C@H]2CN2CCCC2)c1

InChI Key InChIKey=LKABTZYAIGODEL-SANMLTNESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321040   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321040(CHEMBL1165318 | {4-[1-(2,5-Difluoro-benzyl)-1,2,3,...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed