BDBM50321042 1-(2,5-Difluoro-benzyl)-7-[6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazine::CHEMBL1165499

SMILES CN1CCN(CC1)c1ccc(cn1)-c1cnc2NCCN(Cc3cc(F)ccc3F)c2c1

InChI Key InChIKey=UREGRBUCAHGLCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321042   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321042(1-(2,5-Difluoro-benzyl)-7-[6-(4-methyl-piperazin-1...)
Affinity DataIC50:  200nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells by immunoblotting and ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321042(1-(2,5-Difluoro-benzyl)-7-[6-(4-methyl-piperazin-1...)
Affinity DataIC50:  33nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed