BDBM50321055 1-[4-(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazin-7-yl}pyridin-2-yl)piperazin-1-yl]ethanone::CHEMBL1163565

SMILES CC(=O)N1CCN(CC1)c1cc(ccn1)-c1cnc2NCCN(Cc3cc(Cl)ccc3C(F)(F)F)c2c1

InChI Key InChIKey=KPWGSBOUOGDCIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321055   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321055(1-[4-(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,...)
Affinity DataIC50:  17nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321055(1-[4-(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,...)
Affinity DataIC50:  250nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells by immunoblotting and ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed