BDBM50321058 CHEMBL1163518::{1-[(5-Chloro-2-trifluoromethyl)benzyl]-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazin-7-yl}piperidin-1-yl-methanone

SMILES FC(F)(F)c1ccc(Cl)cc1CN1CCNc2ncc(cc12)-c1ccc(cc1)C(=O)N1CCCCC1

InChI Key InChIKey=PWLBHXRORQLROL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321058   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50321058(CHEMBL1163518 | {1-[(5-Chloro-2-trifluoromethyl)be...)
Affinity DataIC50:  121nMAssay Description:Inhibition of ALK by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed