BDBM50323161 (5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1,2-a]pyrimidin-6-yl)methanamine::CHEMBL1209853

SMILES Cc1nc2nc(cn2c(c1CN)-c1ccc(Cl)cc1Cl)-c1ccccc1

InChI Key InChIKey=MMKVMFVAFDJNGK-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50323161   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi:  6nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to DPP-4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human DPP89More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50:  1.90E+4nMAssay Description:inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50:  1.30E+4nMAssay Description:inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50:  1.00E+3nMAssay Description:inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50323161((5-(2,4-dichlorophenyl)-7-methyl-2-phenylimidazo[1...)
Affinity DataIC50: >4.00E+4nMAssay Description:inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed