BDBM50323920 CHEMBL1213975::N-methyl-4-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)phenyl)ureido)phenoxy)picolinamide

SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(CN4CCN(C)CC4)cc3)cc2)ccn1

InChI Key InChIKey=RQLWMLCETYOBRR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323920   

TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(CHEMBL1213975 | N-methyl-4-(4-(3-(4-((4-methylpipe...)
Affinity DataIC50:  572nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(CHEMBL1213975 | N-methyl-4-(4-(3-(4-((4-methylpipe...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(CHEMBL1213975 | N-methyl-4-(4-(3-(4-((4-methylpipe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed