BDBM50323921 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-morpholinoethoxy)phenyl)urea::CHEMBL1213976

SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(OCCN3CCOCC3)cc2)ccc1Cl

InChI Key InChIKey=CYTGCHOMPXDYOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323921   

TargetTyrosine-protein kinase ABL1(Mus musculus)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  244nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  106nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50:  92.3nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed