BDBM50324335 2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,4']bipyridinyl-4-carboxylic Acid Amide::CHEMBL1215220

SMILES NC(=O)c1cc(N[C@@H]2CCNC2)nc(c1)-c1ccnc(NC2CCCCC2)c1

InChI Key InChIKey=WXGCJNLWHYWDFU-QGZVFWFLSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324335   

TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324335(2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324335(2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...)
Affinity DataIC50:  18nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324335(2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed