BDBM50325371 4-(6-(cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(1-(dimethylamino)propan-2-yl)benzamide::CHEMBL1223207

SMILES CC(CN(C)C)NC(=O)c1ccc(cc1)-c1cnc2ccc(NCC3CC3)nn12

InChI Key InChIKey=VDPJIGRDFSBMRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325371   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50325371(4-(6-(cyclopropylmethylamino)imidazo[1,2-b]pyridaz...)
Affinity DataIC50:  73nMAssay Description:Inhibition of purified His-tagged IKK-beta after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50325371(4-(6-(cyclopropylmethylamino)imidazo[1,2-b]pyridaz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant IKKalpha after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed