BDBM50325372 4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(dimethylamino)ethyl)benzamide::CHEMBL588573::TCMDC-136678

SMILES CN(C)CCNC(=O)c1ccc(cc1)-c1cnc2ccc(NCc3ccc(Cl)c(Cl)c3)nn12

InChI Key InChIKey=RIUBYVIQQWWKMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50325372   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50325372(4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyrida...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CDK2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50325372(4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyrida...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of purified His-tagged IKK-beta after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50325372(4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyrida...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant GSK3-beta after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed