BDBM50325788 2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)methoxy)phenyl)acetic acid::CHEMBL1223687

SMILES OC(=O)Cc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1

InChI Key InChIKey=GKHODUKSOBLBHU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325788   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325788(2-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed