BDBM50325956 CHEMBL1223886::N-(3-(1-(3-(1-(3-methoxybenzyl)-1H-benzo[d]imidazol-2-ylamino)propyl)piperidin-4-yl)phenyl)acetamide

SMILES COc1cccc(Cn2c(NCCCN3CCC(CC3)c3cccc(NC(C)=O)c3)nc3ccccc23)c1

InChI Key InChIKey=ATLHSMTXMSHZHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325956   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325956(CHEMBL1223886 | N-(3-(1-(3-(1-(3-methoxybenzyl)-1H...)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHOK1 cells assessed as reduction in [3H]inositol phosphate levels by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325956(CHEMBL1223886 | N-(3-(1-(3-(1-(3-methoxybenzyl)-1H...)
Affinity DataIC50:  180nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHOK1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed