BDBM50326374 (S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-naphthamide::CHEMBL1243374

SMILES O=C(CNC(=O)c1cccc2ccccc12)N1CCC[C@H]1C#N

InChI Key InChIKey=HSIDTMLTVRFYGR-AWEZNQCLSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326374   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326374((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP4 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326374((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP8 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326374((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP9 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326374((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP2 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326374((S)-N-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)-1-na...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human recombinant FAP expressed in Hi5 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed