BDBM50326376 (S)-1-((2S,4R)-4-(2-(isoindolin-2-yl)-2-oxoethyl)-5-oxopyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::CHEMBL1243403

SMILES O=C(C[C@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N)N1Cc2ccccc2C1

InChI Key InChIKey=YNMLXSQEZDAZPZ-IKGGRYGDSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326376   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326376((S)-1-((2S,4R)-4-(2-(isoindolin-2-yl)-2-oxoethyl)-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant FAP expressed in Hi5 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326376((S)-1-((2S,4R)-4-(2-(isoindolin-2-yl)-2-oxoethyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP8 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326376((S)-1-((2S,4R)-4-(2-(isoindolin-2-yl)-2-oxoethyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP4 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326376((S)-1-((2S,4R)-4-(2-(isoindolin-2-yl)-2-oxoethyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP2 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326376((S)-1-((2S,4R)-4-(2-(isoindolin-2-yl)-2-oxoethyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DPP9 expressed in insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed