BDBM50326659 3,10-dimethoxy-17-methyl-(10S)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::3,10-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL606644
SMILES COc1cccc2C[C@H]3N(C)CC[C@@]4(CC(=O)CC[C@@]34OC)c12
InChI Key InChIKey=FXPIRWWMNVRGSD-BHIYHBOVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50326659
Affinity DataKi: 0.700nMAssay Description:Binding affinity by its ability to displace [3H]DAMGO from mu receptor in homogenates of guinea pig brainMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
Affinity DataKi: 1.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity by its ability to displace [3H]-U-69,593 from kappa receptor in homogenates of guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Binding affinity by its ability to displace [3H]DPDPE from delta receptor in homogenates of guinea pig brainMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
Affinity DataKi: 101nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 403nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the presence of NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair