BDBM50328250 4-(2-aminothiazol-4-yl)-7-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)thiazol-2-ylthio)-2H-chromen-2-one::CHEMBL1258481

SMILES Nc1nc(cs1)-c1cc(=O)oc2cc(Sc3ncc(s3)C(O)(C(F)(F)F)C(F)(F)F)ccc12

InChI Key InChIKey=RWPZJWJYQIQHOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328250   

TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328250(4-(2-aminothiazol-4-yl)-7-(5-(1,1,1,3,3,3-hexafluo...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed