BDBM50329498 CHEMBL1271447::N-(6-benzyl-2-(phenethylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)naphthalene-2-sulfonamide

SMILES O=S(=O)(Nc1nc(NCCc2ccccc2)nc2CCN(Cc3ccccc3)Cc12)c1ccc2ccccc2c1

InChI Key InChIKey=MAEKBOFLYVOEBZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329498   

TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329498(CHEMBL1271447 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50:  900nMAssay Description:Inhibition of MLCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329498(CHEMBL1271447 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329498(CHEMBL1271447 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CAMK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329498(CHEMBL1271447 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed