BDBM50330362 (1R,5S)-N-cyclopropyl-N-((2-methoxy-3-methylpyridin-4-yl)methyl)-7-(4-(3-(2-methoxybenzyloxy)propoxy)phenyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide::CHEMBL1276274

SMILES COc1ccccc1COCCCOc1ccc(cc1)C1=C([C@H]2CNC[C@@H](C1)N2)C(=O)N(Cc1ccnc(OC)c1C)C1CC1

InChI Key InChIKey=VDYBDHDHYNXGPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330362   

TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330362((1R,5S)-N-cyclopropyl-N-((2-methoxy-3-methylpyridi...)
Affinity DataIC50:  18nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50330362((1R,5S)-N-cyclopropyl-N-((2-methoxy-3-methylpyridi...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed