BDBM50330705 2-(2-fluorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione::CHEMBL1276163

SMILES Cc1n(C)c(=O)cc2[nH]n(-c3ccccc3F)c(=O)c12

InChI Key InChIKey=SJZNHPLAJCICKZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330705   

TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330705(2-(2-fluorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]...)
Affinity DataKi:  308nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed