BDBM50330713 CHEMBL1275631::N-(3-(4,5-dimethyl-3,6-dioxo-5,6-dihydro-1H-pyrazolo[4,3-c]pyridin-2(3H)-yl)phenyl)acetamide

SMILES CC(=O)Nc1cccc(c1)-n1[nH]c2cc(=O)n(C)c(C)c2c1=O

InChI Key InChIKey=TXSKSMBUQNZLQR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330713   

TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330713(CHEMBL1275631 | N-(3-(4,5-dimethyl-3,6-dioxo-5,6-d...)
Affinity DataKi:  328nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed