BDBM50330721 4-((2-(2-chlorophenyl)-4-methyl-3,6-dioxo-2,3-dihydro-1H-pyrazolo[4,3-c]pyridin-5(6H)-yl)methyl)benzenesulfonamide::CHEMBL1276945

SMILES Cc1n(Cc2ccc(cc2)S(N)(=O)=O)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12

InChI Key InChIKey=LKRBPTRAJWXRMQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330721   

TargetNADPH oxidase 4(Homo sapiens (Human))
Genkyotex

Curated by ChEMBL
LigandPNGBDBM50330721(4-((2-(2-chlorophenyl)-4-methyl-3,6-dioxo-2,3-dihy...)
Affinity DataKi:  259nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed