BDBM50332002 1-(4-(2,4-dichlorophenyl)-4-fluoropiperidin-1-yl)-2-(pyridin-4-ylmethoxy)ethanone::CHEMBL1289681

SMILES FC1(CCN(CC1)C(=O)COCc1ccncc1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=RQSKSHYRVLDTTR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332002   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332002(1-(4-(2,4-dichlorophenyl)-4-fluoropiperidin-1-yl)-...)
Affinity DataEC50:  6.60E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed